Lox
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Composition
Each ml contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 3.0 mg.
Pharmacology
It is a sterile ophthalmic solution containing Ciprofloxacin hydrochloride which is a synthetic and multiple dose fluoroquinolone anti-microbial agent.
Indication
It is highly effective in the treatment of corneal ulcers and conjunctivitis caused by susceptible strains of microorganisms. It is also indicated in the treatment of Keratitis, Kerato-conjunctivitis, Blepharitis, Blepharo- conjunctivitis, Acute Meibomianitis, Dacryocystitis, and Prophylaxis of ocular infections due to Neisseria gonorrhoea or Chlamydia trachomatis, Prevention of ocular infections after removal of a corneal or physical
agent before and after ocular surgery.
Dosage and Administration
Corneal Ulcers: On the first day, instill 2 drops in the affected eye every 15 minutes for the first 6 hours and then 2 drops into the affected eye every 30 minutes for the reminder of the day. On the second day, instill 2 drops in the affected eye hourly. On the third through the fourteenth day, place two drops in the affected eye every four hours. If the patients needed to be treated for more than 14 days, physician should be consulted for opinion but for either indication a maximum duration of 21 days is recommended.
Superficial Ocular Infection/Conjunctivitis:
The usual dose is instillation of 1 or 2 drops into the conjunctival sac of the affected eye every 2 hours while awake for two days and 1 or 2 drops every four hours while awake for the next five days.
Contraindication
Hypersensitivity to quinolones or any component of this product.
Precaution
Prolonged use of Ciprofloxacin may result in overgrowth of nonsusceptible organisms including fungi. Ciprofloxacin should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity reaction.
Side Effect
Local burning or discomfort, itching, foreign body sensation, crystalline precipitates, lid margin crusting, conjunctival hyperemia and a bad taste following administration. Photophobia and nausea may be reported.
Drug Interaction
Specific Drug interaction studies have not been observed with ophthalmic Ciprofloxacin.
Overdose
A topical overdose may be flushed from the eye(s) with warm water.
Store in a cool & dry place, protected from light, use within one month after the first opening & Keep out of the
reach of children.
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