D-Reach

Composition
D-Reach 20000 IU Capsule: Each capsule contains cholecalciferol USP 20000 IU.
D-Reach 40000 IU Capsule: Each capsule contains cholecalciferol USP 40000 IU.
Pharmacology
D-Reach is a preparation of cholecalciferol (Vitamin D 3 ). Vitamin D 3 helps for the absorption & reabsorption of
calcium & phosphorous. Vitamin D 3 is essential for normal bone growth & to maintain bone density. It also
reduces the severity of bacterial infection, improves lung function, prevents the risk of cancer (breast, colorectal)
& helps to maintain adequate insulin levels for type 2 diabetes patients.
Indication
D-Reach is indicated in the treatment & prevention of Vitamin D 3 deficiency. It is also indicated as an adjunct to
specific therapy for osteoporosis in patients with Vitamin D 3 deficiency.
Dosage & Administration
Adults:
Prevention of vitamin D3 deficiency: 20000 IU in every 4 weeks. Higher doses may be required in certain
situations.
Treatment of vitamin D3 deficiency: 40000 IU in once weekly for 7 weeks. Doses for maintenance therapy is
1400-2000 IU/day. To confirm the target level of 25-hydroxy D, measurement of it should be determined 3-4
months after initiating the maintenance therapy.
Addition to specific therapy for osteoporosis: 20000 IU (1 capsule) once a month.
Children (12-18 years):
20000 IU every 6 weeks for prevention of vitamin D 3 deficiency
20000 IU once every 2 weeks for 6 weeks for treatment
Contraindication
It is contraindicated in patients with known hypersensitivity to Vitamin D 3 .
Precaution
It should be used with caution in patients with impaired renal function.
Side Effects
The general side effects are hyperclacaemia, hypercalciuria, skin rash, pruritus, urticaria, nausea, abdominal
pain.
Use in Pregnancy & Lactation
This high strength formulation is not recommended in pregnancy & lactation.
Drug Interaction
It interferes with phenytoin, barbiturates, glucocorticoids, certain laxative (such as liquid paraffin), actinomycin
and imidazole antifungal agents.
Overdose
Overdose can lead to hyper-vitaminosis, hypercalciuria and hypercalcaemia.

Keep below 30° C temperature, protected from light & moisture. Keep out of the reach of children.