LEQUIN (
Levofloxacin) is indicated in the following infectionsl Community-acquired pneumonia due to Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila, or Mycoplasma pneumoniae
• Nosocomial pneumonia due to methicillin-susceptible Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, or Streptococcus pneumoniae
• Acute maxillary sinusitis due to Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis
• Acute exacerbation of chronic bronchitis due to Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis
• Complicated & uncomplicated skin and soft tissue infections due to Staphylococcus aureus, Streptococcus pyogenes, Proteus mirabilis or Enterococcus faecalis
• Chronic bacterial prostatitis due to Escherichia coli, Enterococcus faecalis, or Staphylococcus epidermidis.
• Complicated & uncomplicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, or Staphylococcus saprophyticus
• Acute pyelonephritis caused by Escherichia coli
• Enteric fever caused by Salmonella typhi or Salmonella paratyphi
• Inhalational anthrax treatment and post-exposure prophylaxis.
Audemars Piguet Replica
| Infection |
Daily Dose |
Treatment Duration |
Community-Acquired Pneumonia
|
500 mg |
7-14 days |
| 700 mg |
5 days |
| Nosocomial Pneumonia |
750 mg |
7-14 days |
| Acute Bacterial Sinusitis |
500 mg |
10-14 days |
| 750 mg |
5 days |
| Acute Exacerbation of Chronic Bronchitis |
500 mg |
7days |
Skin and Skin Structure
Infections |
Uncomplicated |
500 mg |
7-10 days |
| Complicated |
750 mg |
7-14 days |
Chronic bacterial prostatitis
|
500 mg |
28 days |
| Urinary Tract Infections |
Uncomplicated |
250 mg |
3 days |
| Complicated |
250 mg |
10 days |
| Pyelonephritis |
250 mg |
10 days |
| Inhalational anthrax ( post-exposure) |
500 mg |
60 days |
LEQUIN (Levofloxacin) can be administered without regard to food but should be administered at least 2 hours before the administration aluminum/magnesium-containing antacids, sucralfate, metal cations such as iron, and multivitamin preparations with zinc.
Patients are advised to drink fluids liberally when received Levofloxacin to avoid crystalluria.
In renal impairment : After initial doses, subsequent doses should be reduced according to Creatinine Clearance (CC) : CC 20-50 ml/ min : ½ of the initial dose, CC 10- 19 ml/ min : ¼ of the initial dose (a regimen of 250 mg daily should be reduced to 125 mg every other day), CC <10 ml/min : initial dose of 250 mg or 500 mg daily reduced to 125 mg every 48 or 24 hrs respectively.
